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Table 4 Clinical and auxological data of the growth response to rhGH according to the parental origin of the retained X chromosome

From: Effect of the parental origin of the X-chromosome on the clinical features, associated complications, the two-year-response to growth hormone (rhGH) and the biochemical profile in patients with turner syndrome

 

Xm (n =  24)

Xp (n =  10)

P

Age at start yr

10.8 ± 2.8

9.9 ± 3.1

0.45

rhGH dose (mg/kg/day)

0,37 ±0.08

0,37 ± 0.02

0.87

Pretreatment height-SDS

−2.81 ± 0.71

−2.66 ± 0.63

0.12

HV during first yr (cm/y)

7.65 ± 1.73

7.87 ± 1.1

0.51

HV during second yr (cm/y)

5.74 ± 1.57

5.59 ± 1.77

0.49

Height-SDS at first yr

−2.21 ± 0.64

−2.25 ± 0.79

0.26

Δ height-SDS

0.55 ± 0.43

0.56 ± 0.41

0.54

  1. According to SDS in relation to national growth chart references for each country. Multiple linear regression analysis was performed with growth response to rhGH treatment parameters as the dependent variables and parental origin of the retained X-chromosome as potentially influencing variable.