Figure 1

Cross-sectional and longitudinal relationships between plasma FGF23 with markers of iron status. Relationship between plasma FGF23 and markers of iron status at baseline (A) where subjects are divided by CRP and with change (∆) overtime (B-D.) where ΔX = log  _e X _post  − log  _e X _pre The equations of the line for A: Subjects with CRP<5 mg/dL = ▲: log_eFGF23 = [7.32 (SE 0.44)] - [0.89 (SE 0.14) (log_eFerr)], R²=38.9%, P≤ 0.0001. Subjects with CRP ≥ 5 mg/dL = ∇ : log_eFGF23 = [2.60 (SE 1. 83)] + [0.39 (SE 0.42)(log_eFerr)], R²=−1.0%, P= 0.4. All subjects together = : log_eFGF23 = [6.44 (SE 0.39)] - [0.57 (SE 0.12) (log_eFerr)], R²=22.3%, P≤ 0.0001. B: Δ FGF23 = [0.08 (SE 0.11)] − [0.41 (SE 0.11)(Δ Ferritin)], R²=14.1%, P= 0.0004. C: Δ FGF23 = [0.07 (SE 0.11)] − [2.22 (SE 0.64)(Δ Haemoglobin)], R²=12.5%, P =0.0008. D: Δ FGF23 = [0.76 (SE 0.22)] + [1.12 (SE 0.26)(Δ Zinc protoporphyrin)], R²=18.6%, P≤ 0.0001.