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Table 2 Mean hormone levels

From: Fulvestrant treatment of precocious puberty in girls with McCune-Albright syndrome

Hormone (units)

Visit

n

Mean ± SD

Median

Free thyroxine (pmol/L)

Screening

30

14.42 ± 2.53

14.65

Thyrotropin (mIU/L)

Screening

30

2.38 ± 3.30

1.53

Estradiol (pmol/L)

Screening

30

20.54 ± 25.59

9.18

 

6 month visit

29

36.10 ± 104.95

9.18

 

12 month visit

26

25.95 ± 30.72

9.55

LH (IU/L)*

Screening

30

0.84 ± 1.04

0.45

 

6 month visit

29

0.10 ± 0.02

0.10

 

12 month visit

28

0.11 ± 0.04

0.10

FSH (IU/L)

Screening

30

3.86 ± 5.42

1.95

 

6 month visit

29

0.82 ± 0.78

0.50

 

12 month visit

29

1.13 ± 1.02

0.60

Testosterone (nmol/L)

Screening

30

0.53 ± 0.19

0.48

 

6 month visit

29

0.56 ± 0.24

0.45

 

12 month visit

28

0.65 ± 0.27

0.66

  1. Prepubertal normal ranges: free thyroxine 10.3-25.7 pmol/L; thyrotropin 0.7-6.4 mIU/L; estradiol < 73.4 pmol/L; LH 0.6-1.6 IU/L; FSH 0.7-6.7 IU/L; testosterone < 0.35-1.2 nmol/L.
  2. * P < 0.005 for median change from baseline to month 12.