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Table 2 HSDS Change from Baseline Stratified by Age at Treatment Start and by Gender

From: Effect of 4 years of growth hormone therapy in children with Noonan syndrome in the American Norditropin Studies: Web-Enabled Research (ANSWER) Program® registry

  Boys Girls
<11 years ≥11 years   <10 years ≥10 years  
N Mean (SD) N Mean (SD) P value N Mean (SD) N Mean (SD) P value
Y1 32 0.53 (0.36) 22 0.24 (0.34) 0.0046 12 0.42 (0.51) 10 0.29 (0.38) 0.5159
Y2 25 0.94 (0.65) 13 0.47 (0.50) 0.0284 6 0.77 (0.55) 5 0.49 (0.67) 0.4726
Y3 16 0.92 (0.65) 10 1.01 (0.65) 0.7168 2 1.24 (0.33) 3 1.24 (0.45) 0.9968
Y4 6 1.15 (0.93) 8 0.90 (0.88) 0.6082 2 1.34 (0.78) 1 1.52 (—)
  1. P values are for comparisons between age groups for each year.
  2. HSDS, height standard deviation score; SD, standard deviation; Y1, year 1; Y2, year 2; Y3, year 3; Y4, year 4.