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Table 1 Baseline demographics by diagnostic category.

From: Identification of factors associated with good response to growth hormone therapy in children with short stature: results from the ANSWER Program®

 

GHD

MPHD

Turner

SGA

ISS

 

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

Gender

          

   Male

543

-

53

-

0

-

33

-

91

-

   Female

155

-

18

-

60

-

17

-

32

-

Age

698

10.9 (3.46)

71

6.4 (5.23)

60

8.5 (4.17)

50

7.1 (3.41)

123

11.2 (2.88)

HSDS

698

-2.2 (0.86)

71

-2.0 (1.36)

60

-2.5 (0.77)

50

-2.8 (0.97)

123

-2.3 (0.68)

IGF-I SDS

605

-2.5 (1.26)

31

-3.2 (1.54)

34

-2.0 (1.43)

32

-2.1 (1.53)

114

-2.2 (1.11)

BMI SDS

681

-0.1 (1.38)

49

0.5 (1.84)

55

0.5 (0.97)

49

-0.8 (1.35)

123

-0.8 (3.38)

Bone Age, yrs

616

9.4 (3.31)

39

8.0 (4.58)

43

7.8 (3.45)

44

6.1 (3.36)

115

9.7 (2.93)

Peak GH, ng/mL

606

5.5 (2.69)

40

3.6 (3.03)

5

12.5 (8.25)

17

13.8 (10.95)

97

15.2 (8.10)

GH dose, μg/kg/day

697

45.9 (10.1)

71

40.6 (11.2)

60

51.9 (9.0)

50

49.9 (13.5)

123

46.1 (8.6)

  1. BMI, body mass index; GH, growth hormone; GHD, growth hormone deficiency; HSDS, height standard deviation score; IGF-I, insulin-like growth factor I; ISS, idiopathic short stature; MPHD, multiple pituitary hormone deficiency; SD, standard deviation; SDS, standard deviation score; SGA, small for gestational age