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Table 2 Sensitivity and Specificity of Percent Reductions in Thyroid Volume at Each Measurement Time Point after Iodine-131 Therapy

From: Prediction of post-treatment hypothyroidism using changes in thyroid volume after radioactive iodine therapy in adolescent patients with Graves' disease

 

Month(s) after iodine-131 therapy

 

1

3

5

8

12

% reduction*

Sens Spec

Sens Spec

Sens Spec

Sens Spec

Sens Spec

30%

75.9 55.0

    

40%

55.2 80.0

79.3 60.0

   

50%

41.4 95.0

75.9 85.0

92.6 53.3

  

60%

 

55.2 90.0

73.3 74.1

96.2 57.9

 

70%

  

51.9 93.3

73.1 78.9

85.2 60.0

80%

   

46.2 94.7

74.1 85.0

90%

    

18.5 100.0

  1. *% reduction: cut-off point for percent reduction in thyroid volume
  2. Sens: sensitivity for predicting hypothyroidism at one year after iodine-131 therapy using %reduction
  3. Spec: specificity for predicting hypothyroidism at one year after iodine-131 therapy using %reduction