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Table 3 Association between HbA1c and bone mineral density measurements, components of the IGF system, bone turnover markers, and dietary intake of calcium and vitamin D

From: Metabolic control and bone health in adolescents with type 1 diabetes

  Spearman correlation coefficient p value* Adjusted p value **
Age 0.24 0.08  
Lumbar Spine BMD † -0.12 0.37 0.63
Volumetric Lumbar Spine † (BMAD) -0.041 0.76 0.85
Femoral neck BMD † -0.056 0.68 0.24
Total body BMD † -0.086 0.53 0.87
% Body fat 0.30 0.02 0.66
IGF-I (ng/ml) -0.15 0.27 0.92
IGFBP3 (μg/L) 0.13 0.37 0.33
IGFBP4 (μg/L) 0.23 0.10 0.1
IGFBP5 (μg/L) -0.09 0.52 0.65
NTX (nM BCE/mM creat) -0.36 0.01 0.73
Bone-specific alkaline phosphatase (μg/L) -0.26 0.06 0.81
Intact PTH (ρg/ml) -0.28 0.04 0.2
Serum 25-hydroxyvitamin D (ng/ml) -0.047 0.74 0.89
Serum Calcium (ml/dL) 0.15 0.28 0.19
Serum Phosphorus (mg/dL) 0.2 0.14 0.01
Serum creatinine (mg/dL) -0.27 0.04 0.007
UCa/uCr 0.27 0.047 0.05
uPhos/uCr 0.22 0.1 0.37
Average vitamin D intake/day (IU) -0.09 0.67 0.55
Average calcium intake/day (mg) -0.13 0.55 0.42
  1. Items in bold p < 0.05.
  2. *Spearman correlation coefficient p value; ** p value adjusted for age, race, and gender; † z-scores