Table 2 Clinical and biochemical features of subjects with T1D
From: Metabolic control and bone health in adolescents with type 1 diabetes
n | FC (n = 30) | PC (n = 27) | p value† | |
|---|---|---|---|---|
Lumbar spine BMD* | 56 | 0.01 (-1.14, 1.07) | -0.46 (-0.82, 0.37) | 0.58 |
Volumetric lumbar spine (BMAD)* | 56 | 0.05 (-0.63, 0.69) | -0.14 (-0.48, 0.57) | 0.83 |
Femoral neck BMD* | 56 | 0.12 (-1.23, 0.98) | -0.48 (-1.19, 1.39) | 0.66 |
Total body BMD* | 56 | 0.46 (-1.27, 1.35) | -0.03 (-1.1, 0.72) | 0.66 |
% body fat | 56 | 28.7 (16.7, 35.3) | 33.7 (20.2, 40) | 0.22 |
IGF-1 (ng/mL) | 56 | 564 (430, 644) | 488 (402, 603) | 0.29 |
IGF BP-3 (μg/L) | 54 | 2883 (2448, 3060) | 2901 (2676, 3436) | 0.36 |
IGF BP-4 (μg/L) | 54 | 398.5 (334.8, 439.2) | 415.5 ± 57.9 | 0.17 |
IGF BP-5 (μg/L) | 54 | 346.0 (300.8, 384.2) | 316.5 (273.2, 447.8) | 0.55 |
NTX (nM BCE/mM creat) | 54 | 238 (98, 366) | 56 (41, 311) | 0.03 |
Bone-Specific Alkaline Phosphatase (ug/L) | 53 | 34 (23, 63) | 19 (14.5, 49.5) | 0.09 |
Intact PTH (ρg/mL) | 53 | 30.5 (21.8, 37.8) | 19 (15, 31) | 0.04 |
Serum 25-hydroxyvitamin D (ng/mL) | 52 | 31 (21, 37) | 32 (24, 38.5) | 0.76 |
Serum Calcium (mg/dL) | 56 | 9.4 (9.3, 9.7) | 9.4 (9.2, 9.6) | 0.99 |
Serum Phosphorus (mg/dL) | 56 | 4.4 (4.1, 5.0) | 4.8 (4.3, 5.2) | 0.21 |
Serum creatinine (mg/dL) | 56 | 0.75 (0.63, 0.8) | 0.7 (0.6, 0.8) | 0.22 |
eGFR estimation (ml/min) | 56 | 137.5 (122.7, 149.8) | 141.8 (118.2, 166.4) | 0.72 |
uCa/uCr | 54 | 0.07[0.05, 0.15] | 0.14[0.09,0.21] | 0.02 |
uPhos/uCr | 54 | 0.80[0.64, 0.92] | 0.90[0.72, 1.0] | 0.22 |
Average vitamin D intake/day (IU) | 25 | 173 (128, 246) | 168 (122, 246) | 1 |
Average calcium intake/day (mg) | 25 | 872 (651, 1136) | 686 (574, 927) | 0.46 |