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Table 2 Clinical and biochemical features of subjects with T1D

From: Metabolic control and bone health in adolescents with type 1 diabetes

  n FC (n = 30) PC (n = 27) p value†
Lumbar spine BMD* 56 0.01 (-1.14, 1.07) -0.46 (-0.82, 0.37) 0.58
Volumetric lumbar spine (BMAD)* 56 0.05 (-0.63, 0.69) -0.14 (-0.48, 0.57) 0.83
Femoral neck BMD* 56 0.12 (-1.23, 0.98) -0.48 (-1.19, 1.39) 0.66
Total body BMD* 56 0.46 (-1.27, 1.35) -0.03 (-1.1, 0.72) 0.66
% body fat 56 28.7 (16.7, 35.3) 33.7 (20.2, 40) 0.22
IGF-1 (ng/mL) 56 564 (430, 644) 488 (402, 603) 0.29
IGF BP-3 (μg/L) 54 2883 (2448, 3060) 2901 (2676, 3436) 0.36
IGF BP-4 (μg/L) 54 398.5 (334.8, 439.2) 415.5 ± 57.9 0.17
IGF BP-5 (μg/L) 54 346.0 (300.8, 384.2) 316.5 (273.2, 447.8) 0.55
NTX (nM BCE/mM creat) 54 238 (98, 366) 56 (41, 311) 0.03
Bone-Specific Alkaline Phosphatase (ug/L) 53 34 (23, 63) 19 (14.5, 49.5) 0.09
Intact PTH (ρg/mL) 53 30.5 (21.8, 37.8) 19 (15, 31) 0.04
Serum 25-hydroxyvitamin D (ng/mL) 52 31 (21, 37) 32 (24, 38.5) 0.76
Serum Calcium (mg/dL) 56 9.4 (9.3, 9.7) 9.4 (9.2, 9.6) 0.99
Serum Phosphorus (mg/dL) 56 4.4 (4.1, 5.0) 4.8 (4.3, 5.2) 0.21
Serum creatinine (mg/dL) 56 0.75 (0.63, 0.8) 0.7 (0.6, 0.8) 0.22
eGFR estimation (ml/min) 56 137.5 (122.7, 149.8) 141.8 (118.2, 166.4) 0.72
uCa/uCr 54 0.07[0.05, 0.15] 0.14[0.09,0.21] 0.02
uPhos/uCr 54 0.80[0.64, 0.92] 0.90[0.72, 1.0] 0.22
Average vitamin D intake/day (IU) 25 173 (128, 246) 168 (122, 246) 1
Average calcium intake/day (mg) 25 872 (651, 1136) 686 (574, 927) 0.46
  1. Items in bold p < 0.05.
  2. † Wilcoxon rank sum test for comparison of continuous variables
  3. * z-scores
  4. Abbreviations: FC: Favorable Control, PC: Poor Control, BMD: bone mineral density, BMAD: bone mineral apparent density, eGFR (estimated glomerular filtration rate)