Table 1 Frequency of genetic subtypes associated with PWS
Subtype | Frequency |
|---|---|
Paternal deletion of chromosome 15q11-q13 (type I or II) | 75% |
Maternal uniparental disomy (UPD) | 24% |
Imprinting center defects (ID) | 1% |
Translocation | < 1% |
Subtype | Frequency |
|---|---|
Paternal deletion of chromosome 15q11-q13 (type I or II) | 75% |
Maternal uniparental disomy (UPD) | 24% |
Imprinting center defects (ID) | 1% |
Translocation | < 1% |