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Table 3 Laboratory and clinical variables before and after intervention in prepubertal and pubertal obese children.

From: Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children

Variables

Prepuberty ()

Puberty ()

 

Preintervention

Postintervention

Preintervention

Postintervention

Height (cm)

137.87 ± 12.66

140.54 ±  12.13***

157.22 ±  10.10†††

158.61 ±  9.59***†††

BMI (kg/m2)

25.62 ± 3.42

24.83 ±  3.63*

28.54 ±  3.96†††

28.02 ±  3.85*†††

Z-score BMI

2.19 ± 0.31

1.98 ±  0.47***

1.96 ±  0.29†††

1.81 ±  0.37***†

Waist (cm)

80.75 ± 9.12

80.02 ± 8.53

90.79 ±  8.43†††

89.70 ±  9.83†††

Waist/Hip Ratio

0.92 ± 0.07

0.92 ± 0.07

0.87 ±  0.06††

0.87 ±  0.07†††

Fat Mass (mm2)a

2405.04 ± 753.91

2166.00 ±  624.89*

3684.20 ±  1178.32††

2654.30 ±  665.60**†

Lean Mass (mm2)a

3411.23 ± 1181.41

3706.65 ± 851.76

5401.10 ±  2144.89

5378.30 ±  1272.13††

SBP (mm Hg)

101.59 ± 12.88

104.37 ± 11.96

111.00 ±  10.22††

109.98 ±  10.48††

DBP (mm Hg)

69.79 ± 10.63

68.79 ± 9.19

70.49 ± 7.99

68.45 ± 8.36

Fasting Glucose (mg/dL)

81.61 ± 9.51

84.09 ± 8.89

83.16 ± 14.41

84.14 ± 14.41

2 Hr pl Glucose (mg/dL)

92.35 ± 13.34

97.68 ± 16.78

100.19 ±  22.45

92.41 ±  17.97*

Fasting Insulin (mU/mL)

9.28 ± 8.74

6.17 ±  5.97*

13.06 ±  8.73

12.25 ±  11.49††

2 Hr pl Insulin (mU/mL)

55.95 ± 66.09

31.57 ±  32.40*

62.23 ±  47.19

55.28 ±  47.03††

HOMA

1.85 ± 1.71

1.31 ±  1.38**

2.77 ±  1.91††

2.43 ±  1.91†††

QUICKI

0.37 ± 0.05

0.40 ±  0.05***

0.34 ±  0.03†††

0.35 ±  0.04*†††

Tg (mg/dL)

115.20 ± 65.65

111.85 ± 59.16

118.24 ± 59.14

112.38 ± 51.76

TC (mg/dL)

171.41 ± 40.49

161.66 ± 31.25

167.40 ± 48.63

158.61 ± 32.19

HDL-C (mg/dL)

38.85 ± 9.19

42.75 ± 12.38

38.70 ± 10.06

43.18 ± 13.22

LDL-C (mg/dL)

113.15 ± 34.78

96.48 ±  26.02*

105.21 ± 45.78

94.10 ± 31.43

Tg/HDL-C

3.12 ± 1.82

2.73 ± 1.62

3.41 ± 2.01

2.78 ± 1.53

CRP (mg/dL)

0.28 ± 0.68

0.13 ± 0.13

0.53 ± 0.82

0.55 ± 1.11

  1. aCalculated in 26 Prepubertal and 10 Pubertal children. , ††, ††† puberty preintervention versus prepuberty preintervention and puberty postintervention versus prepuberty postintervention; *, **, *** postintervention versus preintervention.