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Table 5 Hormonal responses to GnRHag postdexamethasone. Post-GnRHag gonadotropin levels are shown at 4 hr and steroid levels at 22 hr. Mean  SEM (observed range).

From: LH Dynamics in Overweight Girls with Premature Adrenarche and Slowly Progressive Sexual Precocity

  Premature Adrenarche SPPOPA OW-PUB PRE Reference Range [20]
  Basal Post-GnRHag Basal Post-GnRHag Basal Post-GnRHag Basal Post-GnRHag
LH 0.15  0.8 3.1  0.8 0.15  0.0 9.8  2.7 2.0  1.0 38  8.5 <0.15 1.0–7.0
(U/L) (0.15) (0.8–5.9) (0.15) (4.3–19) (0.2–8.2) (4.8–76)   
FSH 1.4  0.2 21.4  3.9 1.1  0.2 26.4  7.3 3.1  0.7 24.9  2.7 0.4–1.7 7.9–32
(U/L) (0.9–2.2) (9.1–42) (0.6–1.8) (23–52) (0.5–6.1) (16.5–32)   
LH/FSH 0.12  0.01 0.16  0.04 0.16  0.03 0.53  0.23 0.46  0.18 1.7  0.50 0.09–0.43 0.04–0.28
(Ratio) (0.07–0.17) (0.05–0.31) (0.08–0.25) (0.10–1.4) (0.09–1.6) (0.15–4.5)   
E2 6.0  1.8 25.8  3.2 6.5  0.5 52.8  13.1 19.0  4.5 134  34.1 ≤5.0–7.0 7.0–49
(pg/mL) (≤5.0–10) (16–39) (≤5.0–8.0) (19–95) (≤5.0–39) (23–298)   
PROG ≤25  0.0 ≤25  0.0 ≤25  0.0 ≤25  0.0 ≤25  0.0 29.8  2.6 ≤25 ≤25
(ng/dl) (25) (25) (25) (25) (25) (25–44)   
17OHP ≤25  0.0 ≤25  0.0 ≤25  0.0 25.8  0.4 ≤25  0.0 73.0  18.2 ≤25 ≤25
(ng/dl) (25) (25) (25) (25–27) (25) (25–172)   
DHEA 121  20.3 98.2  9.5 105  21 80.8  9.9 92.5  17.6 89.6  10.6 28–59 27–69
(ng/dl) (67–212) (77–129) (50–162) (42–96) (41–158) (44–125)   
A'dione 30.1  3.8 28.0  1.6 28.4  3.4 37.9  8.9 43.9  7.9 76.6  17.4 ≤25 25–40
(ng/dl) (≤25–52) (25–35) (25–42) (25–72) (25–88) (25–169)   
Total T ≤10  0.0 ≤10  0.0 12.2  2.3 11.5  0.6 15.2  2.4 18.3  3.5 ≤10 ≤10
(ng/dl) (≤10) (≤10) (10–19) (10–13) (10–30) (10–40)   
Cortisol 2.0  0.3 1.6  0.2 2.0  0.3 1.5  0.3 2.0  0.6 1.5  0.3 1.0–3.0 1.0–5.0
(g/dl) (1.0–3.0) (1.0–2.0) (1.0–3.0) (0.9–2.0) (0.9–2.0) (0.9–3.0)   
  1. versus OW-PUB .05.
  2. versus OW-PUB .01.
  3. versus SPPOPA .05.
  4. Conversions to SI units: DHEA  0.0347  nmol/L; for all other conversions, refer to Table 2.