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Table 4 Study group wake and sleep gonadotropin and estradiol levels. Observed range for each study group is shown, as is 5th–95th percentile reference range of healthy prepubertal volunteers [20].

From: LH Dynamics in Overweight Girls with Premature Adrenarche and Slowly Progressive Sexual Precocity

GROUP LH (U/L) FSH (U/L) Estradiol (pg/mL)
  Mean Wake Peak Sleep Mean Wake Peak Sleep Mean Wake Peak Sleep
PA       
Mean 0.16 0.50 1.3 2.1 7.6 5.5
SEM 0.01 0.22 0.13 0.56 0.88 0.5
Range 0.15–0.20 0.15–1.8 0.85–1.7 1.0–5.2 5.0–10.5 5.0–8.0
SPPOPA       
Mean 0.15 0.68 1.4 2.0 13.1 7.9
SEM 0.00 0.17 0.20 0.41 3.1 1.3
Range 0.15–0.17 0.15–1.2 0.72–1.9 1.1–3.0 5.5–23.0 5.0–12.0
OW-PUB       
Mean 2.6 5.3 4.0 4.4 25.5 28.9
SEM 0.89 1.7 0.87 0.88 4.4 7.2
Range 0.15– 6.9 0.15–13.5 0.68–7.2 0.60–6.8 10.5–43.7 7.0–63.0
Prepubertal       
 Reference Range 0.15 0.150.85 0.401.6 0.53.0 5.016.0 5.09.0
  1. -values versus OW-PUB: .05, .01.