Advertisement
Table 4 Study group wake and sleep gonadotropin and estradiol levels. Observed range for each study group is shown, as is 5th–95th percentile reference range of healthy prepubertal volunteers [20].
From: LH Dynamics in Overweight Girls with Premature Adrenarche and Slowly Progressive Sexual Precocity
| GROUP | LH (U/L) | FSH (U/L) | Estradiol (pg/mL) | |||
|---|---|---|---|---|---|---|
| Mean Wake | Peak Sleep | Mean Wake | Peak Sleep | Mean Wake | Peak Sleep | |
PA 
| ||||||
| Mean |
0.16
|
0.50
|
1.3
| 2.1 |
7.6
|
5.5
|
| SEM | 0.01 | 0.22 | 0.13 | 0.56 | 0.88 | 0.5 |
| Range |
 0.15–0.20
|
 0.15–1.8
| 0.85–1.7 | 1.0–5.2 |
 5.0–10.5
|
 5.0–8.0
|
SPPOPA 
| ||||||
| Mean |
0.15
| 0.68 |
1.4
| 2.0 | 13.1 |
7.9
|
| SEM | 0.00 | 0.17 | 0.20 | 0.41 | 3.1 | 1.3 |
| Range |
 0.15–0.17
|
 0.15–1.2
| 0.72–1.9 | 1.1–3.0 | 5.5–23.0 |
 5.0–12.0
|
OW-PUB 
| ||||||
| Mean | 2.6 | 5.3 | 4.0 | 4.4 | 25.5 | 28.9 |
| SEM | 0.89 | 1.7 | 0.87 | 0.88 | 4.4 | 7.2 |
| Range |
 0.15– 6.9
|
 0.15–13.5
| 0.68–7.2 | 0.60–6.8 | 10.5–43.7 | 7.0–63.0 |
Prepubertal 
| ||||||
| Reference Range |
0.15
| 0.15–0.85 | 0.40–1.6 | 0.5–3.0 |
 5.0–16.0
|
 5.0–9.0
|
-values versus OW-PUB: 
.05, 
.01.
-values versus OW-PUB: 
.05, 
.01.