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Table 1 Outline of study protocol.

From: LH Dynamics in Overweight Girls with Premature Adrenarche and Slowly Progressive Sexual Precocity

Day Clocktime Procedure
Day 1 1900 Overnight hormonal sleep test
Day 2 0800 Baseline sampling begins
   Oral glucose tolerance test
   Pelvic ultrasound examination
  1200 Dexamethasone 0.25 mg/m2 PO
  1600 Basal sample for steroids
  1601 ACTH1-24 (1.0 mcg/m2 IV) test begins
  1700 Basal GnRHag test LH&FSH sampling begins
  1800 GnRHag test (leuprolide 10 mcg/m2 SC) test begins
Day 3 1200 Post-GnRHag 18 hr sampling
  1201 Dexamethasone 0.25 mg/m2 PO
  1400 Post-GnRHag sampling resumes (20 hr)
  1800 GnRHag test sampling ends (24 hr)