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Table 1 Adverse events associated with methimazole.

From: Adverse Events Associated with Methimazole Therapy of Graves' Disease in Children

Age at diagnosis Gender MMI dose at time Duration of therapy Reaction
   of AE (mg/day) at time of AE  
3 5/12 M 10 12 weeks Mild liver injury
4 M 10 32 weeks Myalgias/joint pain/facial urticaria
4 4/12 F 10 2 weeks Pruritis and hives
4 3/4 F 30 2 weeks Stevens-Johnson syndrome
5 1/12 F 7.5 3 weeks Diffuse urticaria
7 10/12 F 15 4 weeks Arthralgia
8 2/12 F 10 2 weeks Rash and joint pain
8 4/12 F 10 3 weeks Urticaria
8 5/12 M 20 9 weeks Arthralgia
8 10/12* M 10 18 months Neutropenia (ANCA+)
8 10/12* M 10 18 months Neutropenia (ANCA−)
10 7/12 M 40 4 weeks Myalgias
11 1/2 F 20 4 weeks Lymphopenia and eosinophilia
12 5/12 F 20 12 weeks Myalgias
12 6/12 F 30 12 weeks Stevens-Johnson syndrome (hospitalization)
14 2/12 F 30 4 weeks Stevens-Johnson, syndrome
15 4/12 F 30 2 weeks Rash
16 11/12 F 20 4 weeks Rash on arms and face
17 6/12 F 30 3 weeks Pruritic rash
  1. * identical twins