Table 3 Percentage changes of individual vital sign parameters following clonidine administration for each study period and overall.
Period | Oxygen saturation (%) | Heart rate | Respiratory rate | ||||||
|---|---|---|---|---|---|---|---|---|---|
|  | Mean | SD | P-value | Mean | SD | P –value | Mean | SD | P -value |
1 | −2.3 | 1.7 | <.001 | −20.8 | 7.8 | <.001 | −32.3 | 17.1 | <.001 |
2 | −2.3 | 2.1 | .001 | −16.7 | 9.6 | .000 | −26.6 | 16.4 | <.001 |
3 | −2.3 | 2.7 | .005 | −8.9 | 23.8 | .170 | −25.6 | 20.8 | .001 |
4 | −1.7 | 1.9 | .010 | −16.6 | 7.4 | .000 | −18.4 | 17.3 | .004 |
Overall | −2.1 | 2.1 | <.001 | −15.9 | 14.3 | <.001 | −26.3 | 18.1 | <.001 |
Period | Systolic blood pressure | Diastolic blood pressure | Â | Â | Â | ||||
| Â | Mean | SD | P -value | Mean | SD | P -value | Â | Â | Â |
1 | −19.1 | 10.8 | .000 | −6.3 | 40.6 | .532 |  |  |  |
2 | −18.8 | 11.1 | .000 | −13.7 | 48.8 | .296 |  |  |  |
3 | −14.6 | 11 | .000 | −22 | 13.4 | .000 |  |  |  |
4 | −20.2 | 16 | .001 | −20.1 | 22.8 | .011 |  |  |  |
Overall | −18.2 | 12.0 | <.001 | −14.7 | 35.6 | .005 |  |  |  |
-value was calculated using a paired 
-test for study periods 1–4; a repeated measurement model with autoregressive correlation structure was used to compute 
-value for overall comparison.
-value was calculated using a paired 
-test for study periods 1–4; a repeated measurement model with autoregressive correlation structure was used to compute 
-value for overall comparison.