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Figure 1 | International Journal of Pediatric Endocrinology

Figure 1

From: Fibroblast Growth Factor 23 (FGF23) and Disorders of Phosphate Metabolism

Figure 1

Structure FGF23 protein. FGF23 is produced as a peptide with 251 amino acids. There is a signal peptide with 24 amino acids, and the secreted FGF23 protein consists of 227 amino acids. A part of FGF23 protein is proteolytically cleaved between 179Arg and 180Ser into inactive fragments by enzymes that recognize 176R-177X-178X-179R motif just before the processing site. FGF homology region is present in the N-terminal portion of this processing site of FGF23.

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