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Table 1 Characteristics and laboratory data of 4 infants with secondary pseudohypoaldosteronism.

From: Transient Pseudohypoaldosteronism due to Urinary Tract Infection in Infancy: A Report of 4 Cases

Patient Age at Serum Na Serum K 17-OH-P Aldosterone Urine Na Urine Renal imaging5
  presentation (mmol/L)1 (mmol/L)1 (nmol/L)2 (nmol/L)3 (mmol/L)4 microbe  
1 29 days 124 8.4 2.15 (71 ng/dL) 33.24 (1200 ng/dL) 54 Group B Streptococcus Unilateral grade 3-4 VUR, mild pelviectasis
2 5 weeks 110 6.8 2.64 (87 ng/dL) 21.74 (785 ng/dL) 12 Klebsiella oxytoca Unilateral hydronephrosis
3 7 months 116 6.7 0.69 (23 ng/dL) 28.67 (1035 ng/dL) 7 Klebsiella pneumoniae Unilateral hydronephrosis and hydroureter
4 3 months 103 7.8 4.85 (160 ng/dL) Not obtained 25 Klebsiella oxytoca Resolution of previous hydronephrosis
4 (event 2) 7 months 111 5.6 Not obtained 9.62 (347 ng/dL) 21 Eschericia coli Atrophic right upper pole versus pyelonephritis
  1. 1Serum sodium and potassium values at the time of presentation to clinic or emergency room. 217-OH-P = Serum 17-alpha hydroxyprogesterone. 3Normal range for serum aldosterone: .083–.44 nmol/L (3–16 ng/dL). 4Urinary sodium was obtained at least one day after the start of antibiotic therapy in all cases expect for Patient 1, in whom the urine sample was obtained the day of antibiotic initiation. 5Renal imaging included renal ultrasound, voiding cystourethrogram (VCUG), and in the case of patient 4 2nd visit, DMSA scan.